Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_12560Transcriptional regulator, IclR family protein; COG1414 Transcriptional regulator. (259 aa)    
Predicted Functional Partners:
ISM_12550
TRAP dicarboxylate transporter, DctQ subunit; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.
 
     0.899
ISM_12555
TRAP dicarboxylate transporter, DctM subunit, putative; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.
 
     0.832
ISM_12545
TRAP dicarboxylate transporter, DctP subunit, putative; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.
 
     0.794
ISM_03330
Hypothetical protein; COG2049 Allophanate hydrolase subunit 1.
  
    0.637
ISM_03325
Urea amidolyase; COG1984 Allophanate hydrolase subunit 2.
  
    0.615
ISM_03940
Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
  
  
  0.538
ISM_14700
COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
    
  0.505
ISM_03915
2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
     
  0.493
ISM_16955
Possible 2-oxoisovalerate dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
     
  0.493
ISM_12565
Flavin-containing monooxygenase FMO; COG2072 Predicted flavoprotein involved in K+ transport.
       0.476
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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