| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_03325 | ISM_03330 | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | 0.999 |
| ISM_03325 | ISM_12560 | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | Transcriptional regulator, IclR family protein; COG1414 Transcriptional regulator. | 0.536 |
| ISM_03330 | ISM_03325 | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | 0.999 |
| ISM_03330 | ISM_12560 | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | Transcriptional regulator, IclR family protein; COG1414 Transcriptional regulator. | 0.570 |
| ISM_03940 | ISM_05020 | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Sorbitol dehydrogenase, putative; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. | 0.489 |
| ISM_03940 | ISM_12560 | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Transcriptional regulator, IclR family protein; COG1414 Transcriptional regulator. | 0.542 |
| ISM_03940 | ISM_14700 | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.838 |
| ISM_05020 | ISM_03940 | Sorbitol dehydrogenase, putative; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. | Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | 0.489 |
| ISM_05020 | ISM_12560 | Sorbitol dehydrogenase, putative; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. | Transcriptional regulator, IclR family protein; COG1414 Transcriptional regulator. | 0.440 |
| ISM_05020 | ISM_14700 | Sorbitol dehydrogenase, putative; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.577 |
| ISM_12545 | ISM_12550 | TRAP dicarboxylate transporter, DctP subunit, putative; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component. | TRAP dicarboxylate transporter, DctQ subunit; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component. | 0.896 |
| ISM_12545 | ISM_12555 | TRAP dicarboxylate transporter, DctP subunit, putative; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component. | TRAP dicarboxylate transporter, DctM subunit, putative; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component. | 0.882 |
| ISM_12545 | ISM_12560 | TRAP dicarboxylate transporter, DctP subunit, putative; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component. | Transcriptional regulator, IclR family protein; COG1414 Transcriptional regulator. | 0.795 |
| ISM_12550 | ISM_12545 | TRAP dicarboxylate transporter, DctQ subunit; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component. | TRAP dicarboxylate transporter, DctP subunit, putative; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component. | 0.896 |
| ISM_12550 | ISM_12555 | TRAP dicarboxylate transporter, DctQ subunit; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component. | TRAP dicarboxylate transporter, DctM subunit, putative; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component. | 0.978 |
| ISM_12550 | ISM_12560 | TRAP dicarboxylate transporter, DctQ subunit; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component. | Transcriptional regulator, IclR family protein; COG1414 Transcriptional regulator. | 0.899 |
| ISM_12550 | ISM_12565 | TRAP dicarboxylate transporter, DctQ subunit; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component. | Flavin-containing monooxygenase FMO; COG2072 Predicted flavoprotein involved in K+ transport. | 0.454 |
| ISM_12550 | ISM_12570 | TRAP dicarboxylate transporter, DctQ subunit; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component. | Endoribonuclease L-PSP family protein; COG0251 Putative translation initiation inhibitor, yjgF family. | 0.414 |
| ISM_12555 | ISM_12545 | TRAP dicarboxylate transporter, DctM subunit, putative; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component. | TRAP dicarboxylate transporter, DctP subunit, putative; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component. | 0.882 |
| ISM_12555 | ISM_12550 | TRAP dicarboxylate transporter, DctM subunit, putative; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component. | TRAP dicarboxylate transporter, DctQ subunit; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component. | 0.978 |