Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_12605CobW; COG0523 Putative GTPases (G3E family). (351 aa)    
Predicted Functional Partners:
ISM_12610
Cobaltochelatase; COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.
 
  
 0.943
ISM_12600
COG5469 Predicted metal-binding protein.
 
    0.926
ISM_12615
CobG; COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
   
 0.852
ISM_12625
COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family.
 
   
 0.851
ISM_12620
precorrin-8X methylmutase; COG2082 Precorrin isomerase.
 
   
 0.807
ISM_12630
COG1010 Precorrin-3B methylase.
 
   
 0.803
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
    
 
 0.755
ISM_12640
precorrin-6Y C5,15-methyltransferase (decarboxylating); COG2241 Precorrin-6B methylase 1.
 
   
 0.744
rpsN
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
 
 
 0.725
folE2
Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
  
  
 0.671
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.