STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_12610Cobaltochelatase; COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases. (1103 aa)    
Predicted Functional Partners:
cobB-2
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 
 0.984
ISM_12620
precorrin-8X methylmutase; COG2082 Precorrin isomerase.
 
  
 0.979
ISM_12640
precorrin-6Y C5,15-methyltransferase (decarboxylating); COG2241 Precorrin-6B methylase 1.
 
  
 0.976
ISM_12625
COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.970
ISM_12630
COG1010 Precorrin-3B methylase.
 
  
 0.969
ISM_12615
CobG; COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
   
 0.965
ISM_08445
cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
  
 0.951
ISM_12605
CobW; COG0523 Putative GTPases (G3E family).
 
  
 0.943
ISM_12600
COG5469 Predicted metal-binding protein.
 
     0.934
ISM_00370
Cobalt chelatase, CobS subunit; COG5271 AAA ATPase containing von Willebrand factor type A (vWA) domain.
     
 0.857
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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