Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_12675COG1396 Predicted transcriptional regulators. (219 aa)    
Predicted Functional Partners:
ISM_12680
COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
     
 0.679
ISM_14135
Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 0.662
cobB
COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.
  
 
  0.640
ISM_06675
Phosphate acetyltransferase; COG0281 Malic enzyme.
    
 0.633
ISM_09586
Malate dehydrogenase; COG0281 Malic enzyme.
    
 0.633
ISM_05375
osmC-like family protein; COG1073 Hydrolases of the alpha/beta superfamily.
  
  
 0.538
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
    
  0.538
ISM_02745
Histidine utilization repressor; COG2188 Transcriptional regulators.
  
  
 0.522
ISM_06265
Transcriptional regulator, GntR family protein; COG2188 Transcriptional regulators.
  
  
 0.522
ISM_13290
COG2188 Transcriptional regulators.
  
  
 0.522
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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