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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_12885Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase. (550 aa)    
Predicted Functional Partners:
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 
0.996
ISM_05245
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.981
ISM_05685
Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
 
 0.974
ISM_00215
Hypothetical protein; COG2199 FOG: GGDEF domain.
 0.971
ISM_04790
Sigma factor sigB regulation protein rsbU; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
  0.942
ISM_01215
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
  0.941
ISM_07425
Putative two-component system sensor histidine kinase; COG2203 FOG: GAF domain.
  
 0.941
ISM_03765
Two component diguanylate cyclase; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
  0.938
ISM_15615
Phosphate regulon transcriptional regulatory protein PhoB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  0.935
ISM_03750
Sigma factor sigB regulation protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
  0.933
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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