Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_12890Hypothetical protein; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides. (97 aa)    
Predicted Functional Partners:
ISM_10541
Hypothetical protein.
  
     0.730
ISM_13235
Hypothetical protein; COG2252 Permeases.
  
     0.691
ISM_06875
Lipoprotein, putative.
  
     0.675
ISM_16505
Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases.
    
 0.449
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
  0.426
ISM_17690
Rep B partitioning protein/ParB-like protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family.
  
     0.425
ISM_06190
Hypothetical protein; COG0516 IMP dehydrogenase/GMP reductase.
  
     0.413
ISM_00285
COG2315 Uncharacterized protein conserved in bacteria.
  
     0.401
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (14%) [HD]