close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_12915Fructose-1,6-bisphosphatase, class II; COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins. (321 aa)    
Predicted Functional Partners:
ISM_13350
COG0021 Transketolase; Belongs to the transketolase family.
   
 0.974
pgi
COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.967
ISM_04665
COG3588 Fructose-1,6-bisphosphate aldolase.
    
 0.959
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
    
 0.948
ISM_14135
Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
     
 0.921
ISM_12910
single-stranded-DNA-specific exonuclease RecJ; COG0608 Single-stranded DNA-specific exonuclease.
       0.820
ISM_12920
COG0460 Homoserine dehydrogenase.
  
    0.717
ISM_06310
COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
    
 0.712
ISM_03915
2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
     
 0.684
ISM_16955
Possible 2-oxoisovalerate dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
     
 0.684
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (32%) [HD]