STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_13085Hypothetical protein; COG4286 Uncharacterized conserved protein related to MYG1 family. (305 aa)    
Predicted Functional Partners:
nuoI
NADH dehydrogenase I, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
    0.721
nuoD
NADH dehydrogenase delta subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
   
    0.678
ISM_13080
NADH-ubiquinone oxidoreductase family protein.
       0.569
ISM_06040
Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
   
    0.551
ISM_01035
Hypothetical protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.
   
    0.537
ISM_14345
NADH dehydrogenase gamma subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
   
    0.537
ISM_05000
COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
   
    0.530
ISM_12320
COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
   
    0.530
ISM_07785
Hypothetical protein; COG3568 Metal-dependent hydrolase.
  
     0.529
ISM_11810
HAD-superfamily subfamily IIA hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.
    
   0.504
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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