Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_13150Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. (170 aa)    
Predicted Functional Partners:
ISM_13145
TPR repeat family protein.
 
     0.735
ISM_13140
DNA-binding protein, putative; COG1396 Predicted transcriptional regulators.
       0.643
ISM_10616
Hypothetical protein.
  
     0.615
ISM_08010
Hypothetical protein.
  
     0.602
ISM_03140
DNA processing protein DprA, putative; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.
   
    0.601
ISM_06565
Competence protein F, putative; COG1040 Predicted amidophosphoribosyltransferases.
  
    0.571
ISM_12050
Diguanylate cyclase, putative; COG2199 FOG: GGDEF domain.
   
    0.551
ISM_11710
Hypothetical protein; COG0500 SAM-dependent methyltransferases.
  
     0.540
ISM_11520
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
   
    0.537
ISM_06870
HD domain protein; COG1896 Predicted hydrolases of HD superfamily.
  
     0.522
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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