Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_13195Hypothetical protein. (336 aa)    
Predicted Functional Partners:
greA
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
       0.834
ISM_15175
COG1426 Uncharacterized protein conserved in bacteria.
  
     0.735
ISM_09601
Hypothetical protein.
  
     0.733
ISM_16045
Hypothetical protein.
  
     0.726
ISM_00675
Acetyltransferase, GNAT family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.
  
     0.723
ISM_06455
Hypothetical protein.
  
     0.718
ISM_00860
Lipoprotein, putative; COG3087 Cell division protein.
  
     0.717
ISM_01180
Hypothetical protein.
  
     0.707
ISM_09971
Rhomboid family protein; COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).
  
     0.702
ISM_03225
Lipoprotein, putative; COG0457 FOG: TPR repeat.
  
     0.700
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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