Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_13275COG3203 Outer membrane protein (porin). (221 aa)    
Predicted Functional Partners:
ISM_15050
COG2825 Outer membrane protein.
  
 
 
 0.792
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
    
 
 0.675
bamA
Outer membrane protein, OMP85 family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
    
 
 0.634
bamD
Competence lipoprotein ComL, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
   
 
 0.627
ISM_09401
PQQ enzyme repeat family protein; COG1520 FOG: WD40-like repeat.
   
 
 0.610
ISM_16365
Lipoprotein, SmpA/OmlA family protein; COG2913 Small protein A (tmRNA-binding).
    
 
 0.599
ISM_06500
PPIC-type PPIASE domain protein; COG0760 Parvulin-like peptidyl-prolyl isomerase.
    
 
 0.579
ISM_14810
Hypothetical protein; COG0760 Parvulin-like peptidyl-prolyl isomerase.
    
 
 0.579
ISM_17140
PPIC-type PPIASE domain; COG0760 Parvulin-like peptidyl-prolyl isomerase.
    
 
 0.579
ISM_00320
COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.
    
 
 0.527
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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