Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_13280Hypothetical protein. (144 aa)    
Predicted Functional Partners:
ISM_09050
Hypothetical protein.
  
     0.619
ISM_13285
Probable hydrolase transmembrane protein; COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold.
       0.584
ISM_07420
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
     0.518
ISM_17110
COG2927 DNA polymerase III, chi subunit.
  
     0.518
ISM_00090
Hypothetical protein.
  
     0.473
ISM_13275
COG3203 Outer membrane protein (porin).
       0.453
ISM_06820
ATP-dependent DNA helicase, UvrD/Rep family protein; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); Belongs to the helicase family. UvrD subfamily.
  
     0.452
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
     0.435
ISM_11960
Hydrolase, NUDIX family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
  
     0.428
ISM_13290
COG2188 Transcriptional regulators.
       0.426
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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