Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_13285Probable hydrolase transmembrane protein; COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold. (253 aa)    
Predicted Functional Partners:
ISM_08180
Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
  
  
 0.727
ISM_13290
COG2188 Transcriptional regulators.
 
     0.721
ISM_13245
Putative mandelate racemase/muconate lactonizing enzyme; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.
    
 0.659
ISM_14885
Xanthine dehydrogenase family protein, small/large subunits; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.
     
  0.640
ISM_04095
Benzoate-coenzyme A ligase; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
     
 0.620
ISM_03595
MviM protein; COG0673 Predicted dehydrogenases and related proteins.
    
 0.612
ISM_13280
Hypothetical protein.
       0.584
ISM_13300
Hypothetical protein; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.
 
     0.577
ISM_13120
Amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.
  
  
  0.572
ISM_10341
N-carbamyl-D-amino acid amidohydrolase; COG0388 Predicted amidohydrolase.
  
  
  0.555
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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