Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ISM_13335Sulfopyruvate decarboxylase subunit alpha; COG4032 Predicted thiamine-pyrophosphate-binding protein. (165 aa)    
Predicted Functional Partners:
ISM_13330
Sulfopyruvate decarboxylase subunit beta; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].
  
  0.999
ISM_13310
COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.
    
  0.730
xsc
Hypothetical protein; Catalyzes the degradation of sulfoacetaldehyde into sulfite and acetyl phosphate. Involved in sulfolactate degradation.
 
  
  0.706
ISM_06675
Phosphate acetyltransferase; COG0281 Malic enzyme.
   
    0.585
ISM_09586
Malate dehydrogenase; COG0281 Malic enzyme.
   
    0.585
ISM_11900
Carboxyvinyl-carboxyphosphonate phosphorylmutase; COG2513 PEP phosphonomutase and related enzymes.
    
 0.567
ISM_13325
TRAP-T family transporter, periplasmic binding protein; COG3181 Uncharacterized protein conserved in bacteria.
  
    0.537
ISM_13655
Hypothetical protein.
  
     0.532
ISM_06830
Nucleotidyltransferase family protein; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).
    
 0.531
ISM_02985
Taurine ABC transporter, permease protein; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.
  
    0.529
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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