STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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Experiments
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[Homology]
Score
ISM_13385Putative beta-lactamase precursor; COG1680 Beta-lactamase class C and other penicillin binding proteins. (382 aa)    
Predicted Functional Partners:
ISM_08155
Flavin-containing monooxygenase; COG2072 Predicted flavoprotein involved in K+ transport.
    
  0.772
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.721
ISM_16420
beta-N-acetylhexosaminidase, putative; COG1472 Beta-glucosidase-related glycosidases.
  
 
 0.685
ISM_16730
Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase.
  
  
 0.578
ISM_17795
Y4BN.
  
  
  0.568
ISM_05675
D-alanyl-D-alaninecarboxypeptidase/D-alanyl-D- alanine-endopeptidase; COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4).
    
 0.545
ISM_16740
Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins.
     
 0.492
ISM_02140
N-acetylmuramoyl-L-alanine amidase, family 2; COG3023 Negative regulator of beta-lactamase expression.
     
 0.454
ISM_09986
Hypothetical protein; COG3409 Putative peptidoglycan-binding domain-containing protein.
     
 0.449
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.448
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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