| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_00215 | ISM_05910 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.987 |
| ISM_00215 | ISM_06925 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.996 |
| ISM_00215 | ISM_09291 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Hypothetical protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.668 |
| ISM_00215 | ISM_09296 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Putative two-component sensor histidine kinase protein; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | 0.748 |
| ISM_00215 | ISM_11185 | Hypothetical protein; COG2199 FOG: GGDEF domain. | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.668 |
| ISM_00215 | ISM_13495 | Hypothetical protein; COG2199 FOG: GGDEF domain. | C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | 0.749 |
| ISM_00215 | ISM_13500 | Hypothetical protein; COG2199 FOG: GGDEF domain. | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.668 |
| ISM_05910 | ISM_00215 | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Hypothetical protein; COG2199 FOG: GGDEF domain. | 0.987 |
| ISM_05910 | ISM_06925 | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.993 |
| ISM_05910 | ISM_09291 | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Hypothetical protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.644 |
| ISM_05910 | ISM_09296 | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Putative two-component sensor histidine kinase protein; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | 0.811 |
| ISM_05910 | ISM_11185 | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.638 |
| ISM_05910 | ISM_13495 | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | 0.811 |
| ISM_05910 | ISM_13500 | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.586 |
| ISM_05920 | ISM_09396 | Hypothetical protein; COG0419 ATPase involved in DNA repair. | Hypothetical protein; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase. | 0.769 |
| ISM_05920 | ISM_13495 | Hypothetical protein; COG0419 ATPase involved in DNA repair. | C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. | 0.755 |
| ISM_05920 | ISM_13500 | Hypothetical protein; COG0419 ATPase involved in DNA repair. | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.546 |
| ISM_05920 | ISM_14590 | Hypothetical protein; COG0419 ATPase involved in DNA repair. | Hypothetical protein. | 0.769 |
| ISM_06925 | ISM_00215 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Hypothetical protein; COG2199 FOG: GGDEF domain. | 0.996 |
| ISM_06925 | ISM_05910 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.993 |