Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_13550Putative kinase/phosphatase; COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism. (154 aa)    
Predicted Functional Partners:
ISM_13565
Phosphocarrier protein HPr; COG1925 Phosphotransferase system, HPr-related proteins.
 
   
 0.959
ISM_13555
Hypothetical protein; Displays ATPase and GTPase activities.
    
 0.933
ISM_13560
PTS system IIA component, Man family protein; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA.
 
   
 0.913
ISM_13545
COG0642 Signal transduction histidine kinase.
       0.845
ISM_13570
Hypothetical protein; COG3176 Putative hemolysin.
       0.700
ISM_13540
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
       0.696
ISM_06995
PTS IIA-like nitrogen-regulatory protein PtsN; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
 
   
 0.665
ISM_13575
Endoribonuclease L-PSP family protein; COG0251 Putative translation initiation inhibitor, yjgF family.
  
    0.635
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
  
 0.617
ISM_01385
Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family.
  
     0.593
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (14%) [HD]