Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_13560PTS system IIA component, Man family protein; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA. (133 aa)    
Predicted Functional Partners:
ISM_13565
Phosphocarrier protein HPr; COG1925 Phosphotransferase system, HPr-related proteins.
 
 
 0.996
ISM_13550
Putative kinase/phosphatase; COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism.
 
   
 0.913
ISM_06995
PTS IIA-like nitrogen-regulatory protein PtsN; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
 
 
 0.880
ISM_13555
Hypothetical protein; Displays ATPase and GTPase activities.
 
   
 0.878
ISM_14135
Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.876
ISM_02820
Phosphomannomutase/phosphoglucomutase; COG1109 Phosphomannomutase.
    
 0.856
ISM_13545
COG0642 Signal transduction histidine kinase.
       0.845
glmM
Phosphoglucomutase/phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
    
 0.751
ISM_07075
COG1004 Predicted UDP-glucose 6-dehydrogenase.
     
  0.739
ISM_13570
Hypothetical protein; COG3176 Putative hemolysin.
       0.708
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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