| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_07350 | ISM_13610 | COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog. | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.597 |
| ISM_09941 | ISM_11525 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. | 0.988 |
| ISM_09941 | ISM_13610 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.668 |
| ISM_09941 | ISM_16740 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.616 |
| ISM_09941 | ISM_16800 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.999 |
| ISM_11525 | ISM_09941 | methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.988 |
| ISM_11525 | ISM_13610 | methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.519 |
| ISM_11525 | ISM_16740 | methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.728 |
| ISM_11525 | ISM_16800 | methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.993 |
| ISM_13595 | ISM_13600 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | 0.905 |
| ISM_13595 | ISM_13605 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | 0.990 |
| ISM_13595 | ISM_13610 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.629 |
| ISM_13595 | ISM_13615 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.850 |
| ISM_13600 | ISM_13595 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | 0.905 |
| ISM_13600 | ISM_13605 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | 0.986 |
| ISM_13600 | ISM_13610 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.629 |
| ISM_13600 | ISM_13615 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.866 |
| ISM_13605 | ISM_13595 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | 0.990 |
| ISM_13605 | ISM_13600 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | 0.986 |
| ISM_13605 | ISM_13610 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.780 |