| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_07350 | ISM_13610 | COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog. | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.565 |
| ISM_08180 | ISM_10720 | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | Hypothetical protein; COG0491 Zn-dependent hydrolases, including glyoxylases. | 0.404 |
| ISM_08180 | ISM_13610 | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.545 |
| ISM_09941 | ISM_13610 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.643 |
| ISM_09941 | ISM_16800 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.996 |
| ISM_10720 | ISM_08180 | Hypothetical protein; COG0491 Zn-dependent hydrolases, including glyoxylases. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.404 |
| ISM_10720 | ISM_13610 | Hypothetical protein; COG0491 Zn-dependent hydrolases, including glyoxylases. | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.618 |
| ISM_13595 | ISM_13600 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | 0.904 |
| ISM_13595 | ISM_13605 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | 0.995 |
| ISM_13595 | ISM_13610 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.632 |
| ISM_13595 | ISM_13615 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.841 |
| ISM_13600 | ISM_13595 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | 0.904 |
| ISM_13600 | ISM_13605 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | 0.993 |
| ISM_13600 | ISM_13610 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.632 |
| ISM_13600 | ISM_13615 | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.864 |
| ISM_13605 | ISM_13595 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | 0.995 |
| ISM_13605 | ISM_13600 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component. | 0.993 |
| ISM_13605 | ISM_13610 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.781 |
| ISM_13605 | ISM_13615 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.915 |
| ISM_13610 | ISM_07350 | Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. | COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog. | 0.565 |