| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_09180 | ISM_12055 | ISM_09180 | ISM_12055 | COG1012 NAD-dependent aldehyde dehydrogenases. | COG1012 NAD-dependent aldehyde dehydrogenases. | 0.662 |
| ISM_09180 | ISM_13620 | ISM_09180 | ISM_13620 | COG1012 NAD-dependent aldehyde dehydrogenases. | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.749 |
| ISM_09180 | ISM_13640 | ISM_09180 | ISM_13640 | COG1012 NAD-dependent aldehyde dehydrogenases. | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.635 |
| ISM_09180 | panC | ISM_09180 | ISM_10516 | COG1012 NAD-dependent aldehyde dehydrogenases. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.773 |
| ISM_10371 | ISM_13620 | ISM_10371 | ISM_13620 | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.929 |
| ISM_10371 | ISM_13635 | ISM_10371 | ISM_13635 | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | COG0167 Dihydroorotate dehydrogenase. | 0.969 |
| ISM_10371 | ISM_13640 | ISM_10371 | ISM_13640 | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.759 |
| ISM_12055 | ISM_09180 | ISM_12055 | ISM_09180 | COG1012 NAD-dependent aldehyde dehydrogenases. | COG1012 NAD-dependent aldehyde dehydrogenases. | 0.662 |
| ISM_12055 | ISM_13620 | ISM_12055 | ISM_13620 | COG1012 NAD-dependent aldehyde dehydrogenases. | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.749 |
| ISM_12055 | panC | ISM_12055 | ISM_10516 | COG1012 NAD-dependent aldehyde dehydrogenases. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.773 |
| ISM_13590 | ISM_13605 | ISM_13590 | ISM_13605 | Hypothetical protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | 0.995 |
| ISM_13590 | ISM_13615 | ISM_13590 | ISM_13615 | Hypothetical protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.853 |
| ISM_13590 | ISM_13620 | ISM_13590 | ISM_13620 | Hypothetical protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.727 |
| ISM_13590 | ISM_13625 | ISM_13590 | ISM_13625 | Hypothetical protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | Transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | 0.631 |
| ISM_13590 | ISM_13635 | ISM_13590 | ISM_13635 | Hypothetical protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | COG0167 Dihydroorotate dehydrogenase. | 0.760 |
| ISM_13590 | ISM_13640 | ISM_13590 | ISM_13640 | Hypothetical protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.608 |
| ISM_13605 | ISM_13590 | ISM_13605 | ISM_13590 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | Hypothetical protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | 0.995 |
| ISM_13605 | ISM_13615 | ISM_13605 | ISM_13615 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. | 0.915 |
| ISM_13605 | ISM_13620 | ISM_13605 | ISM_13620 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.705 |
| ISM_13605 | ISM_13625 | ISM_13605 | ISM_13625 | ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component. | Transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | 0.673 |