close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_13625Transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. (211 aa)    
Predicted Functional Partners:
ISM_13620
N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.
 
     0.804
ISM_13605
ABC transporter, ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.
 
     0.674
ISM_13615
Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases.
 
     0.664
ISM_13590
Hypothetical protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.
 
     0.638
ISM_13600
ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.
 
     0.623
ISM_13595
ABC nitrate/sulfonate/bicarbonate transporter, inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.
 
     0.616
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.544
ISM_13635
COG0167 Dihydroorotate dehydrogenase.
  
     0.511
ISM_13640
Pyridine nucleotide-disulphide oxidoreductase family protein; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
     0.502
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.