Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_13640Pyridine nucleotide-disulphide oxidoreductase family protein; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (444 aa)    
Predicted Functional Partners:
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
 0.999
ISM_13635
COG0167 Dihydroorotate dehydrogenase.
 0.999
ISM_06040
Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
 
 0.986
ISM_13615
Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases.
 
 
 0.964
ISM_15345
Glutamate synthase large subunit-like protein; COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family.
 
 0.931
ISM_14700
COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
   
 0.927
ISM_14325
NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
 
 0.920
ISM_16935
COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family.
 
 0.901
ISM_07475
COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family.
 
 0.886
ISM_15335
Glutamine amidotransferase-like protein; COG0067 Glutamate synthase domain 1.
  
 0.869
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.