| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_03340 | ISM_06335 | COG1802 Transcriptional regulators. | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.755 |
| ISM_03340 | ISM_10296 | COG1802 Transcriptional regulators. | COG1802 Transcriptional regulators. | 0.760 |
| ISM_03340 | ISM_13645 | COG1802 Transcriptional regulators. | Pyruvate dehydrogenase complex repressor; COG2186 Transcriptional regulators. | 0.591 |
| ISM_04310 | ISM_13645 | Regulatory protein GntR, HTH:GntR, C-terminal; COG1802 Transcriptional regulators. | Pyruvate dehydrogenase complex repressor; COG2186 Transcriptional regulators. | 0.658 |
| ISM_06335 | ISM_03340 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | COG1802 Transcriptional regulators. | 0.755 |
| ISM_06335 | ISM_07870 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.706 |
| ISM_06335 | ISM_13645 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | Pyruvate dehydrogenase complex repressor; COG2186 Transcriptional regulators. | 0.510 |
| ISM_07870 | ISM_06335 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.706 |
| ISM_07870 | ISM_10296 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | COG1802 Transcriptional regulators. | 0.653 |
| ISM_07870 | ISM_13645 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | Pyruvate dehydrogenase complex repressor; COG2186 Transcriptional regulators. | 0.460 |
| ISM_08180 | ISM_13635 | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | COG0167 Dihydroorotate dehydrogenase. | 0.746 |
| ISM_08180 | ISM_13645 | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | Pyruvate dehydrogenase complex repressor; COG2186 Transcriptional regulators. | 0.541 |
| ISM_08245 | ISM_13645 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | Pyruvate dehydrogenase complex repressor; COG2186 Transcriptional regulators. | 0.570 |
| ISM_10296 | ISM_03340 | COG1802 Transcriptional regulators. | COG1802 Transcriptional regulators. | 0.760 |
| ISM_10296 | ISM_07870 | COG1802 Transcriptional regulators. | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.653 |
| ISM_10296 | ISM_13645 | COG1802 Transcriptional regulators. | Pyruvate dehydrogenase complex repressor; COG2186 Transcriptional regulators. | 0.470 |
| ISM_13635 | ISM_08180 | COG0167 Dihydroorotate dehydrogenase. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.746 |
| ISM_13635 | ISM_13645 | COG0167 Dihydroorotate dehydrogenase. | Pyruvate dehydrogenase complex repressor; COG2186 Transcriptional regulators. | 0.450 |
| ISM_13645 | ISM_03340 | Pyruvate dehydrogenase complex repressor; COG2186 Transcriptional regulators. | COG1802 Transcriptional regulators. | 0.591 |
| ISM_13645 | ISM_04310 | Pyruvate dehydrogenase complex repressor; COG2186 Transcriptional regulators. | Regulatory protein GntR, HTH:GntR, C-terminal; COG1802 Transcriptional regulators. | 0.658 |