| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_11490 | ISM_13680 | ISM_11490 | ISM_13680 | COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | Hypothetical protein; COG0116 Predicted N6-adenine-specific DNA methylase. | 0.544 |
| ISM_11490 | ISM_14800 | ISM_11490 | ISM_14800 | COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | 0.584 |
| ISM_11490 | pnp | ISM_11490 | ISM_06380 | COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.512 |
| ISM_13680 | ISM_11490 | ISM_13680 | ISM_11490 | Hypothetical protein; COG0116 Predicted N6-adenine-specific DNA methylase. | COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | 0.544 |
| ISM_13680 | ISM_13685 | ISM_13680 | ISM_13685 | Hypothetical protein; COG0116 Predicted N6-adenine-specific DNA methylase. | Hypothetical protein; COG2951 Membrane-bound lytic murein transglycosylase B. | 0.775 |
| ISM_13680 | ISM_13695 | ISM_13680 | ISM_13695 | Hypothetical protein; COG0116 Predicted N6-adenine-specific DNA methylase. | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.560 |
| ISM_13680 | ISM_14800 | ISM_13680 | ISM_14800 | Hypothetical protein; COG0116 Predicted N6-adenine-specific DNA methylase. | COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | 0.544 |
| ISM_13680 | ISM_14980 | ISM_13680 | ISM_14980 | Hypothetical protein; COG0116 Predicted N6-adenine-specific DNA methylase. | GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response. | 0.619 |
| ISM_13680 | ISM_15020 | ISM_13680 | ISM_15020 | Hypothetical protein; COG0116 Predicted N6-adenine-specific DNA methylase. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.735 |
| ISM_13680 | cobD | ISM_13680 | ISM_13690 | Hypothetical protein; COG0116 Predicted N6-adenine-specific DNA methylase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.554 |
| ISM_13680 | leuS | ISM_13680 | ISM_02265 | Hypothetical protein; COG0116 Predicted N6-adenine-specific DNA methylase. | COG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.574 |
| ISM_13680 | pnp | ISM_13680 | ISM_06380 | Hypothetical protein; COG0116 Predicted N6-adenine-specific DNA methylase. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.676 |
| ISM_13680 | pyrG | ISM_13680 | ISM_16790 | Hypothetical protein; COG0116 Predicted N6-adenine-specific DNA methylase. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.551 |
| ISM_13685 | ISM_13680 | ISM_13685 | ISM_13680 | Hypothetical protein; COG2951 Membrane-bound lytic murein transglycosylase B. | Hypothetical protein; COG0116 Predicted N6-adenine-specific DNA methylase. | 0.775 |
| ISM_13685 | ISM_13695 | ISM_13685 | ISM_13695 | Hypothetical protein; COG2951 Membrane-bound lytic murein transglycosylase B. | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.564 |
| ISM_13685 | cobD | ISM_13685 | ISM_13690 | Hypothetical protein; COG2951 Membrane-bound lytic murein transglycosylase B. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.569 |
| ISM_13695 | ISM_13680 | ISM_13695 | ISM_13680 | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Hypothetical protein; COG0116 Predicted N6-adenine-specific DNA methylase. | 0.560 |
| ISM_13695 | ISM_13685 | ISM_13695 | ISM_13685 | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Hypothetical protein; COG2951 Membrane-bound lytic murein transglycosylase B. | 0.564 |
| ISM_13695 | cobD | ISM_13695 | ISM_13690 | Cobalamin biosynthetic protein CobC; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.997 |
| ISM_14800 | ISM_11490 | ISM_14800 | ISM_11490 | COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | 0.584 |