Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_13700COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (121 aa)    
Predicted Functional Partners:
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 
 0.830
ISM_16640
Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific.
  
 0.742
ISM_01200
COG1868 Flagellar motor switch protein.
 
 
 0.678
ISM_00215
Hypothetical protein; COG2199 FOG: GGDEF domain.
  
 0.668
ISM_09921
Autoinducer-binding transcriptional regulator LuxR; COG2771 DNA-binding HTH domain-containing proteins.
  
 
 0.639
ISM_06625
Response regulator; COG0784 FOG: CheY-like receiver.
 
 
 0.633
ISM_12905
Multi-sensor Signal Transduction Histidine Kinase; COG2202 FOG: PAS/PAC domain.
   
 0.616
ISM_11520
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 0.611
ISM_01205
Sensor histidine kinase; COG0591 Na+/proline symporter.
   
 0.593
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
  
 0.586
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.