STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_13720Putative aminotransferase; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities. (390 aa)    
Predicted Functional Partners:
ISM_10685
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 
 0.947
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 
 0.945
ISM_14405
COG2873 O-acetylhomoserine sulfhydrylase.
   
 0.935
ISM_12190
COG0031 Cysteine synthase.
    
 0.926
ISM_13135
COG0436 Aspartate/tyrosine/aromatic aminotransferase.
 
  
0.917
ISM_13465
Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
     
 0.911
ISM_15115
Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain.
     
 0.911
ISM_12920
COG0460 Homoserine dehydrogenase.
    
 0.799
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
 
  0.795
ISM_02350
Cytosol aminopeptidase family protein; COG0260 Leucyl aminopeptidase; Belongs to the peptidase M17 family.
  
 
  0.787
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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