Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ISM_13840Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (231 aa)    
Predicted Functional Partners:
ISM_05000
COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
  
 
  0.777
ISM_04990
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
  0.771
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
  0.767
ISM_04995
COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.
   
 
  0.744
ISM_12315
Putative succinate dehydrogenase membrane anchor; COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
   
 
  0.703
ISM_12320
COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
   
 
  0.701
ISM_12325
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
     
  0.697
ISM_04975
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 
  0.693
ISM_00050
Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
  
  
 
0.646
ISM_04010
Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases.
    
  0.638
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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