Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISM_13960ArsC family protein; COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family. (96 aa)    
Predicted Functional Partners:
ISM_13965
Hypothetical protein.
       0.702
rpoA
DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.694
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
  0.630
ISM_04370
Probable DSBA oxidoreductase; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.
    
   0.594
ISM_15695
DSBA-like thioredoxin family protein; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.
    
   0.594
ISM_05920
Hypothetical protein; COG0419 ATPase involved in DNA repair.
  
     0.583
ISM_08180
Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
    
 
 0.538
ISM_02275
Hypothetical protein; COG1466 DNA polymerase III, delta subunit.
  
     0.527
ISM_13955
COG1278 Cold shock proteins.
       0.506
ISM_09996
Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.
  
     0.421
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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