Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ISM_13970Hypothetical protein. (183 aa)    
Predicted Functional Partners:
ISM_13975
Hypothetical protein.
 
  
 0.986
ISM_13980
COG3220 Uncharacterized protein conserved in bacteria; Belongs to the UPF0276 family.
 
  
 0.985
ISM_13985
Hypothetical protein; COG5572 Predicted integral membrane protein.
 
  
 0.956
mnmG
Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
    
 
 0.719
ISM_12040
Membrane protein, putative.
  
  0.670
ISM_06040
Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
     
  0.621
ISM_10426
COG3258 Cytochrome c.
  
 
  0.579
secY
Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.455
ISM_09401
PQQ enzyme repeat family protein; COG1520 FOG: WD40-like repeat.
     
 0.441
ISM_08760
Thiosulfate sulfurtransferase, putative; COG2897 Rhodanese-related sulfurtransferase.
  
 
 0.424
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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