STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_13980COG3220 Uncharacterized protein conserved in bacteria; Belongs to the UPF0276 family. (285 aa)    
Predicted Functional Partners:
ISM_13975
Hypothetical protein.
  
 0.997
ISM_13985
Hypothetical protein; COG5572 Predicted integral membrane protein.
 
  
 0.989
ISM_13970
Hypothetical protein.
 
  
 0.986
ISM_12040
Membrane protein, putative.
   
    0.698
ISM_17380
COG3702 Type IV secretory pathway, VirB3 components.
   
    0.698
ISM_17375
Type IV secretion system protein B4, putative; COG3451 Type IV secretory pathway, VirB4 components.
   
    0.540
ISM_17330
Hypothetical protein; COG3704 Type IV secretory pathway, VirB6 components.
   
    0.450
msrQ
Hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the [...]
   
  
 0.442
ISM_17345
Conjugal transfer protein; COG2948 Type IV secretory pathway, VirB10 components.
   
    0.410
ISM_10166
COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
   
    0.407
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.