Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
ISM_13980COG3220 Uncharacterized protein conserved in bacteria; Belongs to the UPF0276 family. (285 aa)    
Predicted Functional Partners:
ISM_13975
Hypothetical protein.
  
 0.997
ISM_13985
Hypothetical protein; COG5572 Predicted integral membrane protein.
 
  
 0.991
ISM_13970
Hypothetical protein.
 
  
 0.985
ISM_17380
COG3702 Type IV secretory pathway, VirB3 components.
   
    0.722
ISM_12040
Membrane protein, putative.
   
    0.653
ISM_17375
Type IV secretion system protein B4, putative; COG3451 Type IV secretory pathway, VirB4 components.
   
    0.617
ISM_17330
Hypothetical protein; COG3704 Type IV secretory pathway, VirB6 components.
   
    0.464
msrQ
Hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the [...]
   
  
 0.409
ISM_02180
Hypothetical protein.
  
    0.404
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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