| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_12455 | ISM_14010 | ISM_12455 | ISM_14010 | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glyoxalase family protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.422 |
| ISM_12455 | trpA | ISM_12455 | ISM_03505 | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.871 |
| ISM_12455 | trpB | ISM_12455 | ISM_13910 | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.850 |
| ISM_13995 | ISM_14000 | ISM_13995 | ISM_14000 | COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.832 |
| ISM_13995 | ISM_14005 | ISM_13995 | ISM_14005 | COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.785 |
| ISM_13995 | ISM_14010 | ISM_13995 | ISM_14010 | COG0477 Permeases of the major facilitator superfamily. | Glyoxalase family protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.776 |
| ISM_13995 | ISM_14015 | ISM_13995 | ISM_14015 | COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein; COG0516 IMP dehydrogenase/GMP reductase. | 0.797 |
| ISM_13995 | ISM_14020 | ISM_13995 | ISM_14020 | COG0477 Permeases of the major facilitator superfamily. | Hydrolase, alpha/beta fold family protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.484 |
| ISM_13995 | thrS | ISM_13995 | ISM_13990 | COG0477 Permeases of the major facilitator superfamily. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.561 |
| ISM_14000 | ISM_13995 | ISM_14000 | ISM_13995 | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | COG0477 Permeases of the major facilitator superfamily. | 0.832 |
| ISM_14000 | ISM_14005 | ISM_14000 | ISM_14005 | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.843 |
| ISM_14000 | ISM_14010 | ISM_14000 | ISM_14010 | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Glyoxalase family protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.819 |
| ISM_14000 | ISM_14015 | ISM_14000 | ISM_14015 | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Hypothetical protein; COG0516 IMP dehydrogenase/GMP reductase. | 0.792 |
| ISM_14000 | ISM_14020 | ISM_14000 | ISM_14020 | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Hydrolase, alpha/beta fold family protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.621 |
| ISM_14000 | thrS | ISM_14000 | ISM_13990 | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.666 |
| ISM_14005 | ISM_13995 | ISM_14005 | ISM_13995 | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | COG0477 Permeases of the major facilitator superfamily. | 0.785 |
| ISM_14005 | ISM_14000 | ISM_14005 | ISM_14000 | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.843 |
| ISM_14005 | ISM_14010 | ISM_14005 | ISM_14010 | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Glyoxalase family protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.793 |
| ISM_14005 | ISM_14015 | ISM_14005 | ISM_14015 | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Hypothetical protein; COG0516 IMP dehydrogenase/GMP reductase. | 0.786 |
| ISM_14005 | ISM_14020 | ISM_14005 | ISM_14020 | Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Hydrolase, alpha/beta fold family protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.528 |