Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
ISM_14075Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain. (97 aa)    
Predicted Functional Partners:
ISM_14085
Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.
 
     0.807
ISM_14090
Hypothetical protein.
 
     0.800
ISM_14095
Alcohol dehydrogenase, zinc-containing; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.
  
    0.777
ISM_14080
Mandelate racemase/muconate lactonizing enzyme, putative; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
       0.773
ISM_14100
Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family.
  
 
 0.642
ISM_14070
Mandelate racemase/muconate lactonizing enzyme, putative; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
       0.639
ISM_14065
Mandelate racemase/muconate lactonizing enzyme, putative; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
       0.607
ISM_04040
Hypothetical protein; COG1834 N-Dimethylarginine dimethylaminohydrolase.
 
     0.501
ISM_08375
phytanoyl-CoA dioxygenase family protein; COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin.
 
  
 0.440
ISM_14105
SIS domain protein; COG1737 Transcriptional regulators.
       0.439
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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