STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_14075Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain. (97 aa)    
Predicted Functional Partners:
ISM_14085
Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.
 
     0.808
ISM_14090
Hypothetical protein.
 
     0.802
ISM_14095
Alcohol dehydrogenase, zinc-containing; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.
  
    0.775
ISM_14080
Mandelate racemase/muconate lactonizing enzyme, putative; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
       0.773
ISM_14100
Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family.
  
 
  0.666
ISM_14070
Mandelate racemase/muconate lactonizing enzyme, putative; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
       0.639
ISM_14065
Mandelate racemase/muconate lactonizing enzyme, putative; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
       0.607
rpoH
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
    
   0.532
ISM_02885
COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); Belongs to the sigma-70 factor family.
    
   0.532
rpoD
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.532
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.