Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_14105SIS domain protein; COG1737 Transcriptional regulators. (295 aa)    
Predicted Functional Partners:
ISM_14110
Rieske 2Fe-2S domain protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.
 
     0.915
ISM_14100
Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family.
 
     0.832
ISM_14060
Mandelate racemase/muconate lactonizing enzyme; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.
 
     0.749
ISM_14055
COG0001 Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
     0.723
ISM_14095
Alcohol dehydrogenase, zinc-containing; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.
 
     0.600
ISM_14065
Mandelate racemase/muconate lactonizing enzyme, putative; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
     0.551
ISM_14070
Mandelate racemase/muconate lactonizing enzyme, putative; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
     0.544
ISM_14085
Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.
 
     0.539
ISM_14080
Mandelate racemase/muconate lactonizing enzyme, putative; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
     0.532
ISM_03915
2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
     
  0.524
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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