Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_14140Hypothetical protein; COG1396 Predicted transcriptional regulators. (219 aa)    
Predicted Functional Partners:
ISM_14135
Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.839
ISM_16940
FwdC/FmdC family protein; COG0070 Glutamate synthase domain 3.
 
     0.788
ISM_16945
Glutamine amidotransferase, class II; COG0067 Glutamate synthase domain 1.
 
     0.788
ISM_16935
COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family.
 
     0.780
ISM_15340
GXGXG motif-containing protein; COG0070 Glutamate synthase domain 3.
 
     0.738
fcl
NAD-dependent epimerase/dehydratase family protein; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
    
  0.734
gmd
NAD-dependent epimerase/dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
       0.731
ISM_14130
Polysaccharide biosynthesis protein; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.
       0.731
ISM_15345
Glutamate synthase large subunit-like protein; COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family.
 
     0.714
ISM_16930
COG0174 Glutamine synthetase.
 
    0.708
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.