Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_14180Zinc ABC transporter, periplasmic zinc-binding protein; COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin. (348 aa)    
Predicted Functional Partners:
znuC
Zinc ABC transporter, ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
 
 
 0.997
ISM_14165
High-affinity zinc uptake system membrane protein ZnuB; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components.
 
 
 0.992
ISM_05645
Hypothetical protein; COG3443 Predicted periplasmic or secreted protein.
 
 
 0.972
ISM_14175
COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
 
  
 0.858
ISM_10820
Peptidase, M23/M37 family protein; COG0739 Membrane proteins related to metalloendopeptidases.
  
  
 0.430
ISM_17565
COG0739 Membrane proteins related to metalloendopeptidases.
  
  
 0.430
dksA
dnaK suppressor protein, putative; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.
  
  
 0.419
fur
Transcriptional regulator, Fur family protein; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
 
  
 0.405
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (12%) [HD]