Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_14205COG0546 Predicted phosphatases. (222 aa)    
Predicted Functional Partners:
ISM_02775
D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.
    
 0.859
ISM_09020
Glycolate oxidase, iron-sulfur subunit; COG0247 Fe-S oxidoreductase.
    
 0.854
ISM_09025
Putative glycolate oxidase subunit protein; COG0277 FAD/FMN-containing dehydrogenases.
    
 0.852
ISM_09030
Glycolate oxidase, GlcD subunit; COG0277 FAD/FMN-containing dehydrogenases.
    
 0.852
ISM_14455
COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.851
ISM_05335
HAD-superfamily hydrolase, subfamily IA, variant 1; COG0546 Predicted phosphatases.
  
  
 
0.783
ISM_06835
Hypothetical protein; COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases.
 
  
 0.764
ISM_12005
HAD-superfamily hydrolase, subfamily IA, variant 1 family protein; COG0546 Predicted phosphatases.
     
  0.739
ISM_06310
COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
 
  
 0.705
ISM_14210
Aminotransferase, DegT/DnrJ/EryC1/StrS family protein; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.
    
  0.667
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: medium (48%) [HD]