Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ISM_14210Aminotransferase, DegT/DnrJ/EryC1/StrS family protein; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family. (397 aa)    
Predicted Functional Partners:
ISM_05610
COG1086 Predicted nucleoside-diphosphate sugar epimerases.
 
 
 0.788
ISM_03530
Putative UDP-galactose phosphate transferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
  
 
 0.732
ISM_14205
COG0546 Predicted phosphatases.
    
  0.667
ISM_03525
COG0110 Acetyltransferase (isoleucine patch superfamily).
 
 
 0.614
ISM_16730
Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase.
  
 0.599
ISM_09135
Hypothetical protein.
 
 
 0.572
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
    
 0.555
ISM_06270
Chloramphenicol acetyltransferase, putative; COG0110 Acetyltransferase (isoleucine patch superfamily).
  
 
 0.534
ISM_06910
Exopolysaccharide production protein exoY; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
  
 
 0.504
ISM_16685
COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
  
 
 0.504
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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