| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_02055 | ISM_04105 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.789 |
| ISM_02055 | ISM_14230 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | COG1960 Acyl-CoA dehydrogenases. | 0.547 |
| ISM_02055 | ISM_14245 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.501 |
| ISM_02055 | ISM_14255 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. | 0.503 |
| ISM_02055 | ISM_14265 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | hydroxymethylglutaryl-CoA lyase; COG0119 Isopropylmalate/homocitrate/citramalate synthases. | 0.714 |
| ISM_02055 | ISM_14270 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.760 |
| ISM_02055 | ISM_14745 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | enoyl-CoA hydratase/isomerase family protein; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.789 |
| ISM_04105 | ISM_02055 | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.789 |
| ISM_04105 | ISM_05910 | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.854 |
| ISM_04105 | ISM_06925 | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.902 |
| ISM_04105 | ISM_14230 | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | COG1960 Acyl-CoA dehydrogenases. | 0.668 |
| ISM_04105 | ISM_14245 | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.421 |
| ISM_04105 | ISM_14255 | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. | 0.466 |
| ISM_04105 | ISM_14270 | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.799 |
| ISM_05910 | ISM_04105 | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.854 |
| ISM_05910 | ISM_06925 | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.993 |
| ISM_05910 | ISM_14270 | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.884 |
| ISM_05910 | ISM_14745 | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | enoyl-CoA hydratase/isomerase family protein; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.854 |
| ISM_06925 | ISM_04105 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.902 |
| ISM_06925 | ISM_05910 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.993 |