| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_06100 | ISM_08325 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.932 |
| ISM_06100 | ISM_10795 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Hypothetical protein. | 0.431 |
| ISM_06100 | ISM_14420 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.614 |
| ISM_06100 | ISM_14430 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Hydantoin utilization protein; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. | 0.781 |
| ISM_06100 | ISM_14435 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Probable oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.600 |
| ISM_08325 | ISM_06100 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.932 |
| ISM_08325 | ISM_14425 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit. | 0.751 |
| ISM_08325 | ISM_14430 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Hydantoin utilization protein; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. | 0.686 |
| ISM_10795 | ISM_06100 | Hypothetical protein. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.431 |
| ISM_10795 | ISM_14430 | Hypothetical protein. | Hydantoin utilization protein; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. | 0.400 |
| ISM_14420 | ISM_06100 | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.614 |
| ISM_14420 | ISM_14425 | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit. | 0.805 |
| ISM_14420 | ISM_14430 | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Hydantoin utilization protein; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. | 0.806 |
| ISM_14420 | ISM_14435 | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Probable oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.773 |
| ISM_14420 | ISM_14440 | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Hypothetical protein; COG0607 Rhodanese-related sulfurtransferase. | 0.538 |
| ISM_14425 | ISM_08325 | COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.751 |
| ISM_14425 | ISM_14420 | COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit. | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.805 |
| ISM_14425 | ISM_14430 | COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit. | Hydantoin utilization protein; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. | 0.999 |
| ISM_14425 | ISM_14435 | COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit. | Probable oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.773 |
| ISM_14425 | ISM_14440 | COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit. | Hypothetical protein; COG0607 Rhodanese-related sulfurtransferase. | 0.538 |