Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ISM_14430Hydantoin utilization protein; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. (692 aa)    
Predicted Functional Partners:
ISM_14425
COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit.
 0.999
ISM_14420
COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
 
     0.806
ISM_14435
Probable oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating).
  
    0.789
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
    
 0.777
ISM_08325
Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
    
  0.659
ISM_11230
COG0402 Cytosine deaminase and related metal-dependent hydrolases.
     
  0.615
ISM_14440
Hypothetical protein; COG0607 Rhodanese-related sulfurtransferase.
  
    0.543
tadA
Cytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
     
  0.511
ISM_03330
Hypothetical protein; COG2049 Allophanate hydrolase subunit 1.
    
  0.425
ISM_03325
Urea amidolyase; COG1984 Allophanate hydrolase subunit 2.
    
  0.424
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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