| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_01030 | ISM_06100 | Probable pyridine nucleotide-disulphide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.723 |
| ISM_01030 | ISM_12985 | Probable pyridine nucleotide-disulphide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | COG4311 Sarcosine oxidase delta subunit. | 0.722 |
| ISM_01030 | ISM_14435 | Probable pyridine nucleotide-disulphide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | Probable oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.558 |
| ISM_06100 | ISM_01030 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Probable pyridine nucleotide-disulphide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | 0.723 |
| ISM_06100 | ISM_07875 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.653 |
| ISM_06100 | ISM_09346 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.918 |
| ISM_06100 | ISM_09661 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.918 |
| ISM_06100 | ISM_12985 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG4311 Sarcosine oxidase delta subunit. | 0.793 |
| ISM_06100 | ISM_12990 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | 0.920 |
| ISM_06100 | ISM_14420 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.634 |
| ISM_06100 | ISM_14425 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit. | 0.864 |
| ISM_06100 | ISM_14430 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Hydantoin utilization protein; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. | 0.777 |
| ISM_06100 | ISM_14435 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Probable oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.616 |
| ISM_07875 | ISM_06100 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.653 |
| ISM_07875 | ISM_14435 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Probable oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.587 |
| ISM_09346 | ISM_06100 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.918 |
| ISM_09346 | ISM_12985 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | COG4311 Sarcosine oxidase delta subunit. | 0.979 |
| ISM_09346 | ISM_14435 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Probable oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.799 |
| ISM_09661 | ISM_06100 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.918 |
| ISM_09661 | ISM_12985 | Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family. | COG4311 Sarcosine oxidase delta subunit. | 0.994 |