Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_14455COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)    
Predicted Functional Partners:
ISM_05350
Hydroxypyruvate reductase; COG2379 Putative glycerate kinase.
 
 0.903
ISM_02775
D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.
 
  
 
0.882
ISM_08435
COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.872
ISM_09025
Putative glycolate oxidase subunit protein; COG0277 FAD/FMN-containing dehydrogenases.
   
 0.864
ISM_09030
Glycolate oxidase, GlcD subunit; COG0277 FAD/FMN-containing dehydrogenases.
   
 0.864
ISM_04015
Serine--glyoxylate transaminase, putative; COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase.
  
 
 0.860
ISM_04685
Serine--glyoxylate transaminase, putative; COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase.
  
 
 0.860
ISM_17005
Probable serine-glyoxylate aminotransferase; COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase.
  
 
 0.860
ISM_09020
Glycolate oxidase, iron-sulfur subunit; COG0247 Fe-S oxidoreductase.
    
 0.856
ISM_04025
Threonine aldolase, low-specificity; COG3616 Predicted amino acid aldolase or racemase.
     
 0.852
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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