Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_14490Xanthine dehydrogenase family protein, medium subunit; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs. (287 aa)    
Predicted Functional Partners:
ISM_14485
COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.
 0.999
ISM_14885
Xanthine dehydrogenase family protein, small/large subunits; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.
 0.998
ISM_14480
COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.
 0.995
ISM_14475
Hypothetical protein.
 
     0.925
ISM_15765
XdhC/CoxI family protein; COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family.
 
 
 0.917
ISM_14565
Hypothetical protein; COG2068 Uncharacterized MobA-related protein.
 
  
 0.724
ISM_11085
Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.615
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
     
  0.615
ISM_04465
Probable guanine deaminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.
 
 
  0.608
ISM_02740
Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.
 
 
  0.568
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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