| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_06370 | ISM_08325 | ISM_06370 | ISM_08325 | COG0686 Alanine dehydrogenase; Belongs to the AlaDH/PNT family. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.446 |
| ISM_06370 | ISM_08700 | ISM_06370 | ISM_08700 | COG0686 Alanine dehydrogenase; Belongs to the AlaDH/PNT family. | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.762 |
| ISM_06370 | ISM_14525 | ISM_06370 | ISM_14525 | COG0686 Alanine dehydrogenase; Belongs to the AlaDH/PNT family. | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.629 |
| ISM_06370 | ISM_15805 | ISM_06370 | ISM_15805 | COG0686 Alanine dehydrogenase; Belongs to the AlaDH/PNT family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.959 |
| ISM_08250 | ISM_08325 | ISM_08250 | ISM_08325 | COG3938 Proline racemase; Belongs to the proline racemase family. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.807 |
| ISM_08250 | ISM_08700 | ISM_08250 | ISM_08700 | COG3938 Proline racemase; Belongs to the proline racemase family. | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.870 |
| ISM_08250 | ISM_14525 | ISM_08250 | ISM_14525 | COG3938 Proline racemase; Belongs to the proline racemase family. | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.676 |
| ISM_08250 | proC | ISM_08250 | ISM_11120 | COG3938 Proline racemase; Belongs to the proline racemase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.665 |
| ISM_08325 | ISM_06370 | ISM_08325 | ISM_06370 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG0686 Alanine dehydrogenase; Belongs to the AlaDH/PNT family. | 0.446 |
| ISM_08325 | ISM_08250 | ISM_08325 | ISM_08250 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG3938 Proline racemase; Belongs to the proline racemase family. | 0.807 |
| ISM_08325 | ISM_08700 | ISM_08325 | ISM_08700 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.875 |
| ISM_08325 | ISM_14525 | ISM_08325 | ISM_14525 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.915 |
| ISM_08325 | ISM_14535 | ISM_08325 | ISM_14535 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | 0.796 |
| ISM_08325 | ISM_15805 | ISM_08325 | ISM_15805 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.479 |
| ISM_08325 | proC | ISM_08325 | ISM_11120 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.917 |
| ISM_08700 | ISM_06370 | ISM_08700 | ISM_06370 | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | COG0686 Alanine dehydrogenase; Belongs to the AlaDH/PNT family. | 0.762 |
| ISM_08700 | ISM_08250 | ISM_08700 | ISM_08250 | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | COG3938 Proline racemase; Belongs to the proline racemase family. | 0.870 |
| ISM_08700 | ISM_08325 | ISM_08700 | ISM_08325 | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.875 |
| ISM_08700 | ISM_12075 | ISM_08700 | ISM_12075 | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | Decarboxylase, pyridoxal-dependent; COG0019 Diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.820 |
| ISM_08700 | ISM_14525 | ISM_08700 | ISM_14525 | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.800 |