| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_06540 | ISM_08250 | ISM_06540 | ISM_08250 | Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family. | COG3938 Proline racemase; Belongs to the proline racemase family. | 0.739 |
| ISM_06540 | ISM_08325 | ISM_06540 | ISM_08325 | Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.780 |
| ISM_06540 | ISM_14525 | ISM_06540 | ISM_14525 | Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family. | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.850 |
| ISM_06540 | proC | ISM_06540 | ISM_11120 | Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.773 |
| ISM_06675 | ISM_08700 | ISM_06675 | ISM_08700 | Phosphate acetyltransferase; COG0281 Malic enzyme. | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.613 |
| ISM_06675 | ISM_14525 | ISM_06675 | ISM_14525 | Phosphate acetyltransferase; COG0281 Malic enzyme. | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.613 |
| ISM_08250 | ISM_06540 | ISM_08250 | ISM_06540 | COG3938 Proline racemase; Belongs to the proline racemase family. | Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family. | 0.739 |
| ISM_08250 | ISM_08325 | ISM_08250 | ISM_08325 | COG3938 Proline racemase; Belongs to the proline racemase family. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.798 |
| ISM_08250 | ISM_08700 | ISM_08250 | ISM_08700 | COG3938 Proline racemase; Belongs to the proline racemase family. | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.714 |
| ISM_08250 | ISM_14525 | ISM_08250 | ISM_14525 | COG3938 Proline racemase; Belongs to the proline racemase family. | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.670 |
| ISM_08250 | proC | ISM_08250 | ISM_11120 | COG3938 Proline racemase; Belongs to the proline racemase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.654 |
| ISM_08325 | ISM_06540 | ISM_08325 | ISM_06540 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family. | 0.780 |
| ISM_08325 | ISM_08250 | ISM_08325 | ISM_08250 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG3938 Proline racemase; Belongs to the proline racemase family. | 0.798 |
| ISM_08325 | ISM_08700 | ISM_08325 | ISM_08700 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.782 |
| ISM_08325 | ISM_14525 | ISM_08325 | ISM_14525 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.865 |
| ISM_08325 | ISM_14535 | ISM_08325 | ISM_14535 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | 0.813 |
| ISM_08325 | proC | ISM_08325 | ISM_11120 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.893 |
| ISM_08700 | ISM_06675 | ISM_08700 | ISM_06675 | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.613 |
| ISM_08700 | ISM_08250 | ISM_08700 | ISM_08250 | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | COG3938 Proline racemase; Belongs to the proline racemase family. | 0.714 |
| ISM_08700 | ISM_08325 | ISM_08700 | ISM_08325 | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.782 |