Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_14630Arsenate reductase; COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (170 aa)    
Predicted Functional Partners:
ISM_14635
Transcriptional regulator, ArsR family protein; COG0640 Predicted transcriptional regulators.
  
 0.983
ISM_14625
COG0798 Arsenite efflux pump ACR3 and related permeases.
 
  
 0.929
ISM_14615
NADPH-dependent FMN reductase; COG0431 Predicted flavoprotein.
 
  
 0.882
ISM_14620
COG1393 Arsenate reductase and related proteins, glutaredoxin family.
 
  
 0.856
ISM_07410
COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis.
  
 0.830
ISM_10720
Hypothetical protein; COG0491 Zn-dependent hydrolases, including glyoxylases.
   
 
 0.737
ISM_06815
Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
  
 
 0.692
ISM_07435
COG3118 Thioredoxin domain-containing protein.
  
 
 0.668
ISM_09125
Hypothetical protein.
  
 
 0.660
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
  0.615
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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