| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_06100 | ISM_10156 | ISM_06100 | ISM_10156 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Gamma-glutamyltranspeptidase, putative; COG0405 Gamma-glutamyltransferase. | 0.814 |
| ISM_06100 | ISM_14660 | ISM_06100 | ISM_14660 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Amidohydrolase family protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. | 0.655 |
| ISM_06100 | ISM_14665 | ISM_06100 | ISM_14665 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | 0.659 |
| ISM_06100 | dapF | ISM_06100 | ISM_02695 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.939 |
| ISM_10156 | ISM_06100 | ISM_10156 | ISM_06100 | Gamma-glutamyltranspeptidase, putative; COG0405 Gamma-glutamyltransferase. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.814 |
| ISM_10156 | ISM_14660 | ISM_10156 | ISM_14660 | Gamma-glutamyltranspeptidase, putative; COG0405 Gamma-glutamyltransferase. | Amidohydrolase family protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. | 0.413 |
| ISM_14655 | ISM_14660 | ISM_14655 | ISM_14660 | COG1694 Predicted pyrophosphatase. | Amidohydrolase family protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. | 0.577 |
| ISM_14655 | ISM_14665 | ISM_14655 | ISM_14665 | COG1694 Predicted pyrophosphatase. | Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | 0.451 |
| ISM_14655 | ISM_14670 | ISM_14655 | ISM_14670 | COG1694 Predicted pyrophosphatase. | Hypothetical protein; COG0059 Ketol-acid reductoisomerase. | 0.528 |
| ISM_14660 | ISM_06100 | ISM_14660 | ISM_06100 | Amidohydrolase family protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.655 |
| ISM_14660 | ISM_10156 | ISM_14660 | ISM_10156 | Amidohydrolase family protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. | Gamma-glutamyltranspeptidase, putative; COG0405 Gamma-glutamyltransferase. | 0.413 |
| ISM_14660 | ISM_14655 | ISM_14660 | ISM_14655 | Amidohydrolase family protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. | COG1694 Predicted pyrophosphatase. | 0.577 |
| ISM_14660 | ISM_14665 | ISM_14660 | ISM_14665 | Amidohydrolase family protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. | Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | 0.577 |
| ISM_14660 | ISM_14670 | ISM_14660 | ISM_14670 | Amidohydrolase family protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. | Hypothetical protein; COG0059 Ketol-acid reductoisomerase. | 0.498 |
| ISM_14660 | dapD | ISM_14660 | ISM_02195 | Amidohydrolase family protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. | COG2171 Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. | 0.483 |
| ISM_14660 | dapF | ISM_14660 | ISM_02695 | Amidohydrolase family protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.420 |
| ISM_14665 | ISM_06100 | ISM_14665 | ISM_06100 | Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.659 |
| ISM_14665 | ISM_14655 | ISM_14665 | ISM_14655 | Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | COG1694 Predicted pyrophosphatase. | 0.451 |
| ISM_14665 | ISM_14660 | ISM_14665 | ISM_14660 | Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | Amidohydrolase family protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. | 0.577 |
| ISM_14665 | ISM_14670 | ISM_14665 | ISM_14670 | Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | Hypothetical protein; COG0059 Ketol-acid reductoisomerase. | 0.687 |