Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_14725Hypothetical protein; COG3926 Putative secretion activating protein. (203 aa)    
Predicted Functional Partners:
ISM_14730
Hypothetical protein.
 
    0.957
ISM_14035
Phasin, PhaP.
  
     0.750
ccmE
Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
       0.721
ISM_14735
Cytochrome c-type biogenesis protein CcmF; COG1138 Cytochrome c biogenesis factor.
       0.697
ISM_14740
Cytochrome c biogenesis family protein; Possible subunit of a heme lyase.
       0.697
ISM_00860
Lipoprotein, putative; COG3087 Cell division protein.
  
     0.663
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
       0.663
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.547
ISM_09826
Peptidoglycan binding domain protein; COG2951 Membrane-bound lytic murein transglycosylase B.
  
     0.534
ISM_15965
Hypothetical protein; COG0591 Na+/proline symporter.
  
     0.534
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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