| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_04465 | ISM_14480 | Probable guanine deaminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. | 0.726 |
| ISM_04465 | ISM_14485 | Probable guanine deaminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. | 0.548 |
| ISM_04465 | ISM_14880 | Probable guanine deaminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | Xanthine dehydrogenase family protein, medium subunit; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs. | 0.790 |
| ISM_04465 | ISM_14885 | Probable guanine deaminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | Xanthine dehydrogenase family protein, small/large subunits; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. | 0.802 |
| ISM_14480 | ISM_04465 | COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. | Probable guanine deaminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | 0.726 |
| ISM_14480 | ISM_14485 | COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. | COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. | 0.999 |
| ISM_14480 | ISM_14565 | COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. | Hypothetical protein; COG2068 Uncharacterized MobA-related protein. | 0.735 |
| ISM_14480 | ISM_14880 | COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. | Xanthine dehydrogenase family protein, medium subunit; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs. | 0.979 |
| ISM_14480 | ISM_14885 | COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. | Xanthine dehydrogenase family protein, small/large subunits; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. | 0.932 |
| ISM_14480 | ISM_14890 | COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. | Hypothetical protein; COG1180 Pyruvate-formate lyase-activating enzyme. | 0.435 |
| ISM_14480 | ISM_15765 | COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. | XdhC/CoxI family protein; COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family. | 0.877 |
| ISM_14485 | ISM_04465 | COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. | Probable guanine deaminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | 0.548 |
| ISM_14485 | ISM_14480 | COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. | COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. | 0.999 |
| ISM_14485 | ISM_14565 | COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. | Hypothetical protein; COG2068 Uncharacterized MobA-related protein. | 0.799 |
| ISM_14485 | ISM_14880 | COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. | Xanthine dehydrogenase family protein, medium subunit; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs. | 0.996 |
| ISM_14485 | ISM_14885 | COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. | Xanthine dehydrogenase family protein, small/large subunits; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. | 0.925 |
| ISM_14485 | ISM_14890 | COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. | Hypothetical protein; COG1180 Pyruvate-formate lyase-activating enzyme. | 0.426 |
| ISM_14485 | ISM_15765 | COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. | XdhC/CoxI family protein; COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family. | 0.836 |
| ISM_14565 | ISM_14480 | Hypothetical protein; COG2068 Uncharacterized MobA-related protein. | COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs. | 0.735 |
| ISM_14565 | ISM_14485 | Hypothetical protein; COG2068 Uncharacterized MobA-related protein. | COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs. | 0.799 |