Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_15105Hypothetical protein; COG0822 NifU homolog involved in Fe-S cluster formation. (151 aa)    
Predicted Functional Partners:
ISM_16010
Putative aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
  
 0.996
ISM_00545
Putative heat shock protein DnaJ; COG1076 DnaJ-domain-containing proteins 1.
  
 0.985
ISM_07105
Iron-sulfur cluster-binding protein; COG0633 Ferredoxin.
  
 0.982
ISM_07310
NifS-related protein; COG0520 Selenocysteine lyase.
  
 0.964
ISM_12170
Aminotransferase, class V; COG0520 Selenocysteine lyase.
  
 0.964
ISM_15955
Cysteine desulfurase SufS; COG0520 Selenocysteine lyase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
  
 0.964
ISM_15460
Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
  
 
 0.946
ISM_15975
FeS assembly ATPase SufC; COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.
  
  
 0.941
ISM_08180
Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
  
 0.940
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.939
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (20%) [HD]