| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_00020 | ISM_04010 | ISM_00020 | ISM_04010 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases. | 0.646 |
| ISM_00020 | ISM_13635 | ISM_00020 | ISM_13635 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | COG0167 Dihydroorotate dehydrogenase. | 0.672 |
| ISM_00020 | ISM_15165 | ISM_00020 | ISM_15165 | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.407 |
| ISM_00300 | ISM_15165 | ISM_00300 | ISM_15165 | COG0308 Aminopeptidase N. | Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.530 |
| ISM_04010 | ISM_00020 | ISM_04010 | ISM_00020 | Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases. | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | 0.646 |
| ISM_04010 | ISM_13635 | ISM_04010 | ISM_13635 | Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases. | COG0167 Dihydroorotate dehydrogenase. | 0.458 |
| ISM_04010 | ISM_15165 | ISM_04010 | ISM_15165 | Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases. | Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.484 |
| ISM_04010 | glmS | ISM_04010 | ISM_14195 | Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases. | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.438 |
| ISM_11350 | ISM_15165 | ISM_11350 | ISM_15165 | COG1536 Flagellar motor switch protein. | Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.544 |
| ISM_13635 | ISM_00020 | ISM_13635 | ISM_00020 | COG0167 Dihydroorotate dehydrogenase. | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | 0.672 |
| ISM_13635 | ISM_04010 | ISM_13635 | ISM_04010 | COG0167 Dihydroorotate dehydrogenase. | Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases. | 0.458 |
| ISM_13635 | ISM_15165 | ISM_13635 | ISM_15165 | COG0167 Dihydroorotate dehydrogenase. | Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.667 |
| ISM_13635 | glmS | ISM_13635 | ISM_14195 | COG0167 Dihydroorotate dehydrogenase. | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.465 |
| ISM_15165 | ISM_00020 | ISM_15165 | ISM_00020 | Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | Iron-sulfur cluster-binding protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | 0.407 |
| ISM_15165 | ISM_00300 | ISM_15165 | ISM_00300 | Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | COG0308 Aminopeptidase N. | 0.530 |
| ISM_15165 | ISM_04010 | ISM_15165 | ISM_04010 | Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases. | 0.484 |
| ISM_15165 | ISM_11350 | ISM_15165 | ISM_11350 | Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | COG1536 Flagellar motor switch protein. | 0.544 |
| ISM_15165 | ISM_13635 | ISM_15165 | ISM_13635 | Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | COG0167 Dihydroorotate dehydrogenase. | 0.667 |
| ISM_15165 | ISM_15170 | ISM_15165 | ISM_15170 | Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.518 |
| ISM_15165 | argC | ISM_15165 | ISM_14715 | Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.525 |