Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISM_15175COG1426 Uncharacterized protein conserved in bacteria. (386 aa)    
Predicted Functional Partners:
ISM_10051
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
    0.899
ISM_02750
Rod shape-determining protein MreB; COG1077 Actin-like ATPase involved in cell morphogenesis.
 
 
 0.893
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
  
    0.869
ISM_05580
Hypothetical protein.
  
     0.757
ISM_09601
Hypothetical protein.
  
     0.755
ISM_06085
Helicase, ATP-dependent, putative; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.
  
    0.753
ISM_00675
Acetyltransferase, GNAT family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.
  
     0.750
ISM_13195
Hypothetical protein.
  
     0.735
ISM_16370
Hypothetical protein; COG1399 Predicted metal-binding, possibly nucleic acid-binding protein.
  
     0.718
ISM_01180
Hypothetical protein.
  
     0.717
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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